What is spermicide condom ? Some condoms contain spermicide in their lubricant, with Nonoxynol-9 being a common ingredient. While spermicides contain active ingredients that inactive sperm and help reduce the risk of pregnancy, but condoms containing them are not suitable for everyone. Why might it cause irritation ? Nonoxynol-9 may be irritating for some people. After use, local dryness, stinging, …