Polyurethane (PU) Condoms vs. Latex Condoms: Strengths and Weaknesses PU Condoms Definition: A polyurethane condomas a type of barrier from pregnancy and STIs, is made of flexible sythetic material, which is thin and strong. They are FDA-approved as an alternative for individuals with latex allergies. PU condoms are typically thinner, odorless, and compatible with a wider range of lubricants compared to …